Usage of Bilanac M
Bilanac M is indicated in the treatment of:
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Allergic rhinitis (seasonal and perennial)
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Chronic urticaria
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Allergic conjunctivitis
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Atopic dermatitis (adjunct)
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Mild asthma with allergic component
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Allergy-related nasal and skin symptoms unresponsive to monotherapy
Mechanism of Action
🔹 Bilastine (20 mg):
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Selectively blocks H1 histamine receptors
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Rapid onset and long-lasting (24-hour) anti-allergic action
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Non-sedating with minimal CNS penetration
🔹 Montelukast (10 mg):
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Inhibits cysteinyl leukotriene receptors (CysLT1)
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Prevents leukotriene-mediated bronchoconstriction, mucus secretion, and inflammation
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Useful in allergic rhinitis and asthma
The combination ensures dual-pathway control:
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Histamine blockade (immediate-phase allergic response)
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Leukotriene suppression (late-phase allergic inflammation)
Key Benefits
✅ Superior control of nasal and ocular symptoms
✅ Effective in nasal congestion, where antihistamines alone are weak
✅ Non-sedating – safe for daytime use
✅ Improves sleep quality and quality of life
✅ Once-daily dosing for high patient compliance
Common Side Effects
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Headache
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Drowsiness (rare with bilastine)
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Abdominal discomfort or dry mouth
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Fatigue (in sensitive individuals)
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Rash (rare)
Precautions
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Avoid in patients with known hypersensitivity to either drug
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Use cautiously in hepatic impairment
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Not recommended in pregnancy and lactation without physician approval
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Avoid alcohol and CNS depressants to reduce potential drowsiness
