Thiodol TP
Thiodol TP - Image 2
Thiodol TP - Image 3
,

Thiodol TP

Composition:

  • Etodolac IP 400 mg

  • Tolperisone Hydrochloride 150 mg
    Therapeutic Class:

  • NSAID + Centrally Acting Muscle Relaxant
    Schedule: Schedule H (Prescription Only)

Thiodol TP is a synergistic combination of Etodolac, a selective anti-inflammatory agent, and Tolperisone, a centrally acting skeletal muscle relaxant. This combination is ideal for managing painful musculoskeletal conditions associated with inflammation and muscle spasm, offering effective relief with a favorable gastrointestinal safety profile.

Usage of Thiodol TP

Indicated for:

  • Acute musculoskeletal pain

  • Low back pain and lumbago

  • Cervical and lumbar spondylosis

  • Sciatica and radiculopathies

  • Post-traumatic pain with muscle spasm

  • Post-operative orthopedic pain

  • Osteoarthritis and rheumatoid arthritis with spasticity

Mechanism of Action

Etodolac:

  • A preferential COX-2 inhibitor, it inhibits prostaglandin synthesis, reducing pain and inflammation

  • Offers effective anti-inflammatory action with reduced risk of gastric mucosal damage compared to traditional NSAIDs

Tolperisone:

  • Acts centrally by blocking voltage-gated sodium channels and stabilizing neuronal membranes

  • Inhibits spinal reflexes and reduces muscle hypertonicity without causing sedation

Combined Action:

  • Targets both inflammation and muscle spasm

  • Enhances mobility and functional recovery

Key Benefits

✅ Dual relief: inflammation + muscle spasm
✅ Less gastric irritation compared to traditional NSAID combos
✅ Non-sedative muscle relaxation – suitable for daytime use
✅ Effective in acute and chronic orthopedic pain
✅ Improves mobility and quality of life

Common Side Effects

  • Gastric discomfort, nausea

  • Mild headache or dizziness

  • Drowsiness (rare)

  • Dry mouth or fatigue

Serious GI bleeding or hepatotoxicity is uncommon at recommended doses.

Precautions

  • Use with caution in patients with peptic ulcer disease, liver dysfunction, or renal impairment

  • Not recommended during pregnancy or breastfeeding

  • Caution in elderly or those on anticoagulants/antiplatelets

  • Discontinue if allergic reactions, GI bleeding, or signs of hepatotoxicity occur

Drug Interactions

  • Avoid concurrent use with other NSAIDs or corticosteroids

  • Tolperisone may interact with CNS depressants or alcohol

  • Monitor INR if used with warfarin or other anticoagulants

Dosage and Administration

  • 1 tablet twice daily after meals

  • Therapy duration: Short-term use (up to 7–10 days) unless otherwise directed

  • Swallow whole; do not crush or chew

Storage

  • Store in a cool, dry place below 25°C

  • Keep away from moisture and direct sunlight

  • Keep out of reach of children

Patient Counseling Points

  • Take after meals to reduce gastric irritation

  • Avoid alcohol during treatment

  • Report any signs of GI bleeding, rash, or persistent fatigue

  • Do not drive if feeling dizzy or drowsy

  • Avoid self-extension of therapy beyond prescribed duration

Related products

Review My Order

0

Subtotal

Taxes & shipping calculated at checkout

Checkout